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Photodynamic therapy for prostate cancer—an emerging approach for organ‐confined disease
Author(s) -
Moore Caroline M.,
Emberton Mark,
Bown Stephen G.
Publication year - 2011
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.21104
Subject(s) - photodynamic therapy , prostate cancer , medicine , prostate , phototoxicity , cancer , biochemistry , chemistry , organic chemistry , in vitro
Since the first report of the use of photodynamic therapy (PDT) for prostate cancer in 1990 it has been investigated as a primary and a salvage treatment, using either whole gland or focal approaches. Since 1990 advances in the transperineal approach to the prostate, coupled with photosensitizers which have a short drug‐light interval and minimal skin phototoxicity, have resulted in major advances in the field. This review will look at the work done to date, and the ongoing studies which help to define the place of PDT as a useful treatment modality for organ‐confined prostate cancer. Lasers Surg. Med. 43:768–775, 2011. © 2011 Wiley‐Liss, Inc.