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Histologic evaluation of the pulsed Nd:YAG laser for laser lipolysis
Author(s) -
Ichikawa Kota,
Miyasaka Muneo,
Tanaka Rica,
Tanino Ryuzaburo,
Mizukami Kana,
Wakaki Moriaki
Publication year - 2005
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.20118
Subject(s) - laser , irradiation , nd:yag laser , scanning electron microscope , materials science , microscopy , biomedical engineering , human skin , ablation , pathology , medicine , optics , biology , physics , nuclear physics , composite material , genetics
Background and Objectives Laser lipoplasty with pulsed Nd:YAG laser, widely used in Europe and Latin America, has recently been introduced in Japan and the USA. We report histologic analyses of the effects of the laser on human fat tissue. Study Design/Materials and Methods Freshly excised human skin and subcutaneous fat were irradiated with the pulsed Nd:YAG laser (SmartLipo, DEKA, Italy). A 1,064 nm laser at 40 Hz and 150 mJ and 100 microseconds‐long pulses were used. Methods of exposure were the same as in the clinical application. In the control group, the specimens were cannulated by the handpiece without irradiation. The tissue was studied by scanning electron microscopy and hematoxylin eosin staining. Results Scanning electron microscopy after irradiation showed greater destruction of human adipocytes than in the control. Degenerated cell membrane, vaporization, liquefaction, carbonization, and heat‐coagulated collagen fibers were observed. Conclusions Our study showed that the SmartLipo appeared to be histologically effective for destruction of human fat tissue. Lasers Surg. Med. 36:43–46, 2005. © 2005 Wiley‐Liss, Inc.