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Clinical and preclinical photodynamic therapy
Author(s) -
Fisher Anita M. R.,
Murphree A. Linn,
Gomer Charles J.
Publication year - 1995
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.1900170103
Subject(s) - photodynamic therapy , photobiology , medicine , treatment modality , photosensitizer , dermatology , medical physics , chemistry , surgery , photochemistry , optics , physics , organic chemistry
Photodynamic therapy (PDT) is a treatment modality that utilizes a photosensitizing drug activated by laser generated light, and is proving effective for oncologic and nononcologic applications. This report provides an overview of photosensitizers, photochemistry, photobiology, and the lasers involved in photodynamic therapy. Clinical and preclinical PDT studies involving Photofrin and various second generation photosensitizers are reviewed. © 1995 Wiley‐Liss, Inc.