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Tissue optical property measurements: Overestimation of absorption coefficient with spectrophotometric techniques
Author(s) -
Torres Jorge H.,
Welch Ashley J.,
Çilesiz Inci,
Motamedi Massoud
Publication year - 1994
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.1900140307
Subject(s) - attenuation coefficient , absorption (acoustics) , property (philosophy) , analytical chemistry (journal) , materials science , chemistry , optics , chromatography , physics , composite material , philosophy , epistemology
This study examines the validity of optical property measurements by comparing surface temperatures rises predicted by a well‐tested mathematical model with temperatures measured experimentally during laser irradiation. Analysis is based on the early temperature response that is proportional to the absorption coefficient. The results of the investigation suggest that values for tissue absorption coefficient can be greatly overestimated when current Spectrophotometric techniques are used. This seems especially true when a broad light beam and a low port‐to‐beam‐size ratio are used for transmission and reflection measurements with an integrating sphere. © 1994 Wiley‐Liss, Inc.