Premium
CO 2 ‐welded venous anastomosis: Enhancement of weld strength with heterologous fibrin glue
Author(s) -
Cikrit Dolores F.,
Dalsing Michael C.,
Weinstein Todd S.,
Palmer Kevin,
Lalka Stephen G.,
Unthank Joseph L.
Publication year - 1990
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.1900100611
Subject(s) - anastomosis , fibrin glue , fibrin , vein , glue , jugular vein , anatomy , surgery , materials science , medicine , composite material , immunology
Abstract The milliwatt CO 2 laser was used to perform end‐to‐end anastomoses in canine jugular veins. There was a high disruption rate (50%) in laser‐welded veins (n = 10). Fibrin glue (n = 17), formed from human fresh‐frozen plasma, enhanced the weld strength decreasing the disruption rate (18%), resulting in an 82% patency which nearly equaled the contralateral sutured vein patency (93%). The bursting strength was improved with fibrin glue. Transmural necrosis was present initially in all groups but extended for a longer distance in the vessel wall in laser‐welded anastomoses. Sutured anastomoses exhibited a greater inflammatory response. In laser‐welded anastomoses endothelial cells were not as confluent as in sutured anastomoses by six weeks. Carbon dioxide laser‐welded end‐to‐end vein anastomoses appear to be impractical because they disrupt too easily. However, the addition of heterologous fibrin glue to the weld results in a reasonably strong anastomosis with histologic properties that may be beneficial in vein bypass grafts.