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Pulsed laser angioplasty: Wavelength power and energy dependencies relevant to clinical application
Author(s) -
Litvack Frank,
Grundfest Warren S.,
Goldenberg Tsvi,
Laudenslager James,
Pacala Thomas,
Segalowitz Jacob,
Forrester James S.
Publication year - 1988
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.1900080111
Subject(s) - angioplasty , laser , medicine , wavelength , materials science , optics , cardiology , optoelectronics , physics
Despite the theoretical advantages of submicrosecond pulsing for clinical laser angioplasty systems, the optimal laser parameters for clinical application are undefined. Further, the enormous peak powers achieved by submicrosecond pulses destroy available fiberoptics. We irradiated 797 segments of cadaver atherosclerotic aorta with nanosecond pulses at 266, 308, 355, 532, and 1064 nanometers. Effective cutting occurred at lower energy fluences in the ultraviolet than in the visible or infrared. For 308 nanometers, at any energy density, number of pulses to perforation was relatively independent of power density. Therefore, long‐pulse ultraviolet wavelengths which could be transmitted through fiberoptics were identified as well suited for a clinical, submicrosecond pulsed laser angioplasty system.