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Effects of Nd: YAG laser photoradiation on intra‐abdominal tissues: A histological study of tissue damage versus power density applied
Author(s) -
Brackett Kim A.,
Sankar M. Y.,
Joffe Stephen N.
Publication year - 1986
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.1900060206
Subject(s) - spleen , pancreas , necrosis , pancreatitis , penetration (warfare) , pathology , medicine , surgery , operations research , engineering
Liver, spleen, and pancreas were subjected to laser photoradiation of 50– to 100‐Watt power levels. Samples were evaluated by light microscopy at 0 hours and 7, 14, and 21 days. Four zones of cellular damage were visible in liver and pancreas: coagulum, cavitation, acidophilia, and transition. Only the first three zones were clearly visible in the spleen. Mean lateral tissue penetration was 3.1 mm in liver, 3.3 mm in spleen, and 1.0 mm in pancreas. No significant increase in lateral penetration occurred with increasing power. Normal healing was observed in liver and spleen. Pancreatitis was found in all samples at 7 days postoperatively. At power levels of 80 W or less, recovery was observed. Above 80 W, pancreatic pseudocysts and necrosis led to death of the animals.