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Microvascular anastomosis using the milliwatt CO 2 laser
Author(s) -
Quigley Matthew R.,
Bailes Julian E.,
Kwaan Hau C.,
Cerullo Leonard J.,
Brown J. Thomas,
Lastre Clara,
Monma Dean
Publication year - 1985
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.1900050403
Subject(s) - adventitia , anastomosis , histology , artery , laser , neointima , surgical anastomosis , medicine , biomedical engineering , anatomy , surgery , pathology , restenosis , stent , optics , physics
The milliwatt CO 2 laser was used to anastomose small vessels in a rat femoral artery model. The technique requires multiple brief applications of 60–70 mW after placement of three equidistant 10–0 nylon stay sutures. The vessel histology is described immediately and 1, 3, 7, and 21 days after the procedure. The laser effects tissue bonding through changes in the collagen of the adventitia and media. Subsequent healing consists of new collagen deposition in the adventitia and re‐endothelialization of the intima associated with neointimal proliferation at 3 weeks.