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Investigation of carcinogenic effects of in Vitro Argon and CO 2 laser exposure of fibroblasts
Author(s) -
Apfelberg David B.,
Mittelman Harry,
Chadi Benny,
Maser Morton R.,
Lash Harvey
Publication year - 1984
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.1900040209
Subject(s) - laser , in vitro , carcinogen , histology , malignant transformation , pathology , argon , chemistry , medicine , biology , optics , genetics , physics , organic chemistry
Mouse heteroploid fibroblasts were grown nine future generations in vitro tissue culture. The cells were exposed to argon laser, CO 2 laser, and x‐ray. Results of scoring for mangnant transformation foci were tabulated and compared. Lasers did not produce a significant malignant transformation. Clinical laser use is reviewed and histology as well as long‐term clinical experience confirms the safety of lasers.