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Carbon Dioxide Laser Treatment of Vaginal Adenosis in DES‐Exposed Offspring: A Prospective Study
Author(s) -
Bellina Joseph H.,
Fischer Ross Lynne,
Hemmings Robert,
Voros Janos I.,
Moorehead Myron
Publication year - 1983
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.1900030104
Subject(s) - offspring , carbon dioxide laser , incidence (geometry) , medicine , population , dysplasia , gynecology , obstetrics , physiology , pregnancy , biology , environmental health , laser , genetics , physics , laser surgery , optics
Seventy‐nine patients with history and physical findings characteristic of antenatal DES exposure were randomly divided into two groups. Fourty‐four DES‐exposed offspring had their vaginal adenosis treated with the carbon dioxide laser (group I), and the remaining 35 DES‐exposed offspring (group II) did not receive any specific treatment for this condition. Additionally, the 79 DES‐exposed offspring were compared to an age‐matched control population (group III). Treatment of vaginal adenosis with the carbon dioxide laser did not significantly reduce the incidence of development of new dysplasia in the DES‐exposed offspring. This study also showed no statistical difference (p ≤ 0.05) in the incidence of dysplasia in DES‐exposed offspring as compared to a control population.