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Angiogenesis three months after clinical transmyocardial laser revascularization using an excimer laser
Author(s) -
van der Sloot Jos A.P.,
Huikeshoven Menno,
van der Wal Allard C.,
Tukkie Raymond,
van Gemert Martin J.C.,
van der Meulen Jan,
Beek Johan F.
Publication year - 2001
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.1130
Subject(s) - scars , medicine , ectasia , neovascularization , excimer laser , revascularization , angiogenesis , excimer , laser , surgery , cardiology , myocardial infarction , optics , physics
Background and Objective We present for the first time histologic findings 3 months after clinical transmyocardial laser revascularization using a XeCl excimer laser. Study Design/Materials and Methods Histology was performed on a patient who died from a noncardiac cause 3 months post‐excimer TMLR. Results In the treated myocardium, no patent channels were found but scars were seen with a linear distribution and in continuity with circumscribed small fibrotic endocardial and epicardial scars. The scars were highly vascularized by new vessels, ranging from small capillaries to large thin walled, and sometimes branching ectatic vessels. Sprouting of vessels into the adjacent myocardium was also observed. Conclusion These results suggest that angiogenesis might play a role in the clinical improvement after TMLR. Lasers Surg. Med. 29:369–373, 2001. © 2001 Wiley‐Liss, Inc.