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Evaluation of myocardial perfusion and left ventricular function six months after percutaneous transmyocardial laser revascularization: Comparison of two Ho‐YAG laser systems with the same wavelength, but different energy delivery and navigation systems
Author(s) -
Strehblow Christoph,
Gyöngyösi Mariann,
Khorsand Aliasghar,
Sperker Wolfgang,
Gatterer Melanie,
Graf Senta,
Sochor Heinz,
Glogar Dietmar
Publication year - 2003
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.10230
Subject(s) - medicine , perfusion , revascularization , cardiology , percutaneous , angina , scintigraphy , nuclear medicine , surgery , myocardial infarction
Background and Objectives Myocardial perfusion and left ventricular function (LVF) were assessed after percutaneous transmyocardial laser revascularization (PTMR) in patients not amenable to conventional revascularization, with a comparison of two laser systems. Study Design/Materials and Methods PTMR was performed with an Eclipse laser in 15 patients, and with a Biosense DMR in 10 patients. 201 Thallium scintigraphy, coronary angiography, and ventriculography were performed at baseline and at the 7.5±4.3‐month follow‐up. All patients in the Biosense DMR group and 10 in the Eclipse group underwent NOGA mapping before PTMR and after follow‐up. Results The event‐free survival rates were comparable, and the angina scores of all patients improved significantly, but more so in the Biosense DMR group than in the Eclipse group (1.2±1.1 vs. 2.3±0.9, P < 0.05). Both, the electrical activity assessed by NOGA mapping and the normalized 201 thallium uptake at redistribution improved significantly in the treated segments after Biosense DMR, while the global LVF decreased insignificantly in the Eclipse group. Conclusions PTMR resulted in significant improvements in the clinical symptoms, but the electrical activity improved only in the Biosense DMR group, without transforming to a better LVF. Lasers Surg. Med. 33:273–281, 2003. © 2003 Wiley‐Liss, Inc.