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Improvement of macromolecular clearance via lymph flow in hamster gingiva by low‐power carbon dioxide laser‐irradiation
Author(s) -
Shimotoyodome Akira,
Okajima Miyuki,
Kobayashi Hisataka,
Tokimitsu Ichiro,
Fujimura Akira
Publication year - 2001
Publication title -
lasers in surgery and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.888
H-Index - 112
eISSN - 1096-9101
pISSN - 0196-8092
DOI - 10.1002/lsm.10004
Subject(s) - carbon dioxide laser , hamster , lymph , pathology , albumin , irradiation , medicine , chemistry , laser , optics , physics , laser surgery , nuclear physics
Background and Objective Although therapeutic effects of low‐power laser‐irradiation on periodontal disease have been reported, little is known about the biological effects of laser‐irradiation in the gingiva. Recently we reported that topical warming stimulated macromolecular clearance via lymph flow in hamster gingiva. This study was conducted to investigate whether low‐power laser‐irradiation affects macromolecular clearance via the lymph flow in the gingiva. Study Design/Materials and Methods We injected 14 C‐methylated albumin into the mandibular gingiva of anesthetized hamsters followed by topical carbon dioxide (CO 2 ) laser‐irradiation (30 seconds, 0.5–1.5 W). We measured the clearance of radiolabeled albumin from the gingiva and its drainage into submandibular lymph nodes during 10 minutes. Results The clearance of the radiolabeled albumin from the gingiva and the influx into the submandibular lymph nodes were increased by CO 2 laser‐irradiation. Conclusion Low‐power CO 2 laser‐irradiation improves macromolecular clearance via the lymph flow in hamster gingiva. Lasers Surg. Med. 29:442–447, 2001. © 2001 Wiley‐Liss, Inc.