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Photoactivation of Extracellular‐Signal‐Regulated Kinase Signaling in Target Cells by Femtosecond Laser (Laser Photonics Rev. 12(7)/2018)
Author(s) -
Wang Shaoyang,
Liu Yaohui,
Zhang Dapeng,
Chen Shihchi,
Kong SiuKai,
Hu Minglie,
Cao Youjia,
He Hao
Publication year - 2018
Publication title -
laser and photonics reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.778
H-Index - 116
eISSN - 1863-8899
pISSN - 1863-8880
DOI - 10.1002/lpor.201870030
Subject(s) - photostimulation , femtosecond , extracellular , laser , microbiology and biotechnology , optogenetics , signal transduction , kinase , mapk/erk pathway , signal (programming language) , materials science , optoelectronics , biology , optics , physics , neuroscience , computer science , programming language
Photostimulation In article number 1700137 , Minglie Hu, Hao He, and co‐workers demonstrate that a single‐time short flash of femtosecond‐laser stimulation on any target cells can activate the extracellular signal‐regulated kinase (ERK) signaling pathway directly, without any optogenetics or exogenous materials. This optical activation is non‐invasive, controllable, and precise in both spatial and temporal dimensions.