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Terahertz Thermometry: Combining Hyperspectral Imaging and Temperature Mapping at Terahertz Frequencies
Author(s) -
Naccache Rafik,
Mazhorova Anna,
Clerici Matteo,
Piccoli Riccardo,
Khorashad Larousse Khosravi,
Govorov Alexander O.,
Razzari Luca,
Vetrone Fiorenzo,
Morandotti Roberto
Publication year - 2017
Publication title -
laser and photonics reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.778
H-Index - 116
eISSN - 1863-8899
pISSN - 1863-8880
DOI - 10.1002/lpor.201600342
Subject(s) - terahertz radiation , hyperspectral imaging , photothermal therapy , chemical imaging , optics , materials science , measure (data warehouse) , image resolution , biological system , physics , computer science , artificial intelligence , database , biology
The accurate and non‐invasive determination of multiple physical parameters, with well‐defined spatial resolution, is crucial for applications in manufacturing, chemistry, medicine and biology. Specifically, the ability to simultaneously measure both temperature and spectral signatures is still experimentally unavailable. To this end, we propose a mapping technique for biological systems, which exploits a linear correlation between terahertz wave reflectivity and temperature, and allows to spatially and spectrally resolve thermal distributions. This method is applied to a model biological system in two relevant cases where in one example, nanoplasmonic‐induced photothermal effects are imaged gaining new insights into collective heating phenomena. In the second example, we demonstrate a joint thermal‐hyperspectral imaging approach to chemically map the presence of a model drug formulation and simultaneously investigate its thermal stability in our biological system. This concept can be easily extended and widely applied to all materials that demonstrate a measurable change in their dielectric properties.