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Sialographic Analysis of Radioiodine‐Associated Chronic Sialadenitis
Author(s) -
Thorpe Ryan K.,
Foggia Megan J.,
Marcus Kathryn S.,
Policeni Bruno,
Maley Joan E.,
Hoffman Henry T.
Publication year - 2021
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.29279
Subject(s) - sialography , medicine , sialadenitis , stenosis , parotid gland , submandibular gland , retrospective cohort study , salivary gland , radiology , gastroenterology , pathology
Objectives/Hypothesis To apply a novel sialography classification system to identify parotid and submandibular ductal findings following I‐131 therapy and to assess correlates to dose and duration of symptoms. Study Design Retrospective single‐center case series. Methods Patients who underwent sialography between February 2008 and February 2019 after previously receiving I‐131 treatment were identified via a retrospective chart review. Their sialograms were systematically evaluated and scored by applying the Iowa parotid sialogram scale to also include submandibular gland analysis. Results From 337 sialograms, 30 (five submandibular, 25 parotid) underwent analysis. Ductal stenosis was identified in all sialograms and was graded as moderate (>50%–75%) in 7/30 cases and severe (>75%) in 15/30 cases. The distal (main) duct was narrowed in 23/30 cases. No association was identified between degree of ductal stenosis and I‐131 dose ( P = .39), age ( P = .81), or time from I‐131 therapy to sialogram ( P = .97). Conclusions The Iowa parotid sialogram scale was successfully applied to report abnormalities of the parotid and submandibular ductal system. The most common manifestation of I‐131‐associated sialadenitis was a severe stenosis within the distal salivary duct. No statistically significant association was found between degree of ductal stenosis and dose of I‐131, age, or duration of symptoms. Level of Evidence 4 Laryngoscope , 131:E1450–E1456, 2021