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Squamous Cell Carcinoma of Nasal Vestibule and Pyramid: Outcomes and Reconstructive Strategies
Author(s) -
Lambertoni Alessia,
Cherubino Mario,
Battaglia Paolo,
De Col Alessia,
Giovannardi Marta,
Antogi Paolo,
Valdatta Luigi,
Karligkiotis Apostolos,
Bignami Maurizio,
Castelnuovo Paolo,
TurriZai Mario
Publication year - 2021
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.29107
Subject(s) - medicine , nasal vestibule , retrospective cohort study , surgery , cohort , stage (stratigraphy) , nasal cavity , biology , paleontology
Objectives Squamous cell carcinoma of nasal vestibule and pyramid is rare, thus classification, treatment protocol, and indications for elective neck treatment are still controversial. Nasal reconstruction is challenging, as well, and prosthesis is still used. Study Design Retrospective cohort study. Methods Retrospective review of patients surgically treated from 2010 to 2018 in a single Institution. Advanced tumors were further treated with adjuvant irradiation. Reconstruction strategy included grafts, locoregional and free flaps, and was customized on layers removed. Results Forty‐five patients were enrolled. The 5‐year overall survival and disease‐free survival were 81.9% ± 7.45% and 61.9% ± 9.09%, respectively. Wang's classification, site of origin, extent of surgery and margins status significantly correlated with prognosis and recurrence rate. Regional recurrences occurred in patients affected by advanced tumors who did not receive any form of elective neck treatment. Conclusion Multidisciplinary management and a proper reconstructive algorithm are recommended. Adjuvant irradiation and elective neck treatment should be advocated for advanced stage high‐risk patients. Level of Evidence 4. Laryngoscope , 131:E1198–E1208, 2021