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Primary Laryngeal Blastomycosis: Diagnostic Challenges and Advances in a Rare Cause of Laryngitis
Author(s) -
Cates Daniel J.,
Rosen Clark A.,
Yassin Mohamed H.,
Smith Libby J.
Publication year - 2019
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.27593
Subject(s) - blastomycosis , blastomyces dermatitidis , medicine , blastomyces , larynx , laryngitis , dermatology , biopsy , pathology , surgery
Blastomyces dermatitidis is a fungal organism endemic to the central and southern United States and capable of causing numerous diseases. Primary blastomycosis of the larynx is a rare clinical entity with a limited number of reported cases in the literature. Diagnosis is challenging as a result of nonspecific physical exam findings, difficulty of histopathologic detection and culture, and need for operative laryngeal biopsy for definitive identification. Molecular and serologic testing is not widely available. The authors present a case of laryngeal blastomycosis, the diagnosis of which was facilitated by in‐office biopsy, and discuss diagnostic challenges. Laryngoscope , 129:2531–2533, 2019