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Depth of invasion in superficial oral tongue carcinoma quantified using intraoral ultrasonography
Author(s) -
Iida Yoshiyuki,
Kamijo Tomoyuki,
Kusafuka Kimihide,
Omae Katsuhiro,
Nishiya Yukio,
Hamaguchi Noriko,
Morita Kotaro,
Onitsuka Tetsuro
Publication year - 2018
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.27305
Subject(s) - medicine , tongue , carcinoma , radiology , metastasis , cancer , nuclear medicine , pathology
Objective Depth of invasion (DOI) in oral carcinoma has been integrated into the primary tumor categories in the current tumor‐node‐metastasis staging (8th edition). However, there is no standard modality to determine DOI preoperatively. The aims of the present study were to evaluate the accuracy of a preoperative measurement of DOI using ultrasonography (US) for superficial oral tongue carcinomas, and to correlate the values obtained with histologically determined DOI measurements. Methods We retrospectively analyzed the records of 56 patients with oral tongue carcinoma who underwent intraoral US preoperatively, followed by curative surgery at the Shizuoka Cancer Center Hospital in Japan. For the measurement of DOI with US, our unique technique (water balloon method) was evaluated. Results The histologically measured tumor size (maximum diameter) showed a distribution of 7.0 to 40.0 mm (mean, 18.6 mm). The correlation between the US‐obtained and histologically obtained DOIs was significant (r = 0.867; P < 0.001). In tumors characterized histologically as superficial (DOI ≤ 5 mm), a significant correlation was observed between US‐obtained and histologically obtained DOIs (r = 0.870, P < 0.001). For the entire cohort, the sensitivity and specificity of US assessment of DOI of ≤ 5 mm or > 5 mm were 92.3% and 70.6%, respectively. Conclusion Intraoral US provides sufficient accuracy for the measurement of tumor DOI in oral tongue carcinoma and is complementary in assessing superficial lesions. Level of Evidence 4. Laryngoscope , 128:2778–2782, 2018