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Propionibacterium acnes as an emerging pathogen in skull base osteomyelitis: A case series
Author(s) -
Schopper Heather K.,
Hatch Jonathan L.,
Meyer Ted A.
Publication year - 2018
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.26869
Subject(s) - propionibacterium acnes , medicine , bacteriology , osteomyelitis , pathogen , pseudomonas aeruginosa , skull , human pathogen , microbiology and biotechnology , dermatology , surgery , bacteria , immunology , biology , acne , genetics
Skull base osteomyelitis (SBO) is recognized as a potentially life‐threatening infection that has been classically attributed to Pseudomonas aeruginosa . However, growing data shows that the bacteriology of SBO is changing. Traditionally thought of as commensal bacterium, P. acnes has been implicated as a serious pathogen in other specialties. Building on a previous case report from our institution, we have identified three patients with SBO who are culture‐positive for Propionibacterium acnes as a single isolate. Herein, we describe the clinical history of the three patients, along with treatment, present outcome, and review of the literature. Laryngoscope , 128:332–335, 2018