Premium
Nasopharyngeal papillomas treated with CO 2 laser and human papillomavirus vaccination
Author(s) -
Cai Yi,
Merea Valeria S.,
Lee Andrew H.,
Su Gloria H.,
Caruana Salvatore M.
Publication year - 2017
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.26580
Subject(s) - medicine , vaccination , human papillomavirus , recurrent respiratory papillomatosis , surgery , laser therapy , laser , pathology , physics , optics
This case report describes the use of CO2 laser and quadrivalent human papillomavirus (HPV) vaccination in two patients with nasopharyngeal HPV11‐positive recurrent respiratory papillomas (RRP). These patients initially underwent CO2 laser excision but developed recurrent lesions and underwent HPV vaccination as adjunct therapy. The recurrent lesions shrank after vaccination and were again excised with CO2 laser. Subsequently, these patients had no recurrence of lesions on long‐term follow‐up at 33 months or 6 years after surgery. Thus, in patients with nasopharyngeal RRP, resection with CO2 laser, and HPV vaccination as adjunct therapy should be considered in HPV11‐associated cases. Laryngoscope , 127:2279–2281, 2017