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Upper airway stimulation therapy: A novel approach to managing obstructive sleep apnea
Author(s) -
Soose Ryan J.,
Gillespie M. Boyd
Publication year - 2016
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.26258
Subject(s) - medicine , obstructive sleep apnea , hypoglossal nerve , airway , stimulation , apnea , clinical trial , sleep apnea , medline , anesthesia , physical therapy , tongue , pathology , political science , law
Objectives Review the role of upper airway stimulation (UAS) therapy in the management of moderate to severe obstructive sleep apnea (OSA). Data Sources A literature search was performed of PubMed and Medline using the search terms clinical trial; obstructive sleep apnea; upper airway stimulation; hypoglossal stimulation; hypoglossal nerve; Inspire; and ImThera. Review Methods All published clinical trials of currently available devices were reviewed. Unpublished data were excluded. Results UAS therapy results in surgical success (AHI decrease of >50% and overall AHI <= 20) in 66% of implanted subjects. In addition, UAS therapy results in significant improvement in daytime sleepiness, snoring, and sleep‐related quality of life. Conclusion UAS therapy is a valid alternative for select patients with moderate to severe OSA who are unsuccessful users of CPAP therapy. Laryngoscope , 126:S5–S8, 2016