z-logo
Premium
Systematic review of surgery for persistent pediatric tracheocutaneous fistula
Author(s) -
Lewis Sean,
Arjomandi Hamid,
Rosenfeld Richard
Publication year - 2017
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.26080
Subject(s) - medicine , confidence interval , surgery , meta analysis , dehiscence , adverse effect , wound dehiscence , cochrane library , incidence (geometry) , systematic review , medline , subcutaneous emphysema , pneumothorax , physics , political science , law , optics
Objectives To compare the treatment outcomes and adverse event rates for primary closure compared to simple excision with healing by secondary intention for persistent tracheocutaneous fistula (TCF) in children. Study Design Systematic review. Methods Systematic review using Preferred Reporting Items for Systematic Reviews and Meta‐Analyses reporting standards. MEDLINE, Embase, Cochrane Library, and manual search were used to identify articles. Inclusion criteria were case series or comparative studies of surgery for persistent TCF in children under age 18 years. Exclusion criteria were age 18 years or older, duplicate patient series, case series with less than two patients, or case reports. Data were pooled using random effects meta‐analysis to assess outcomes, adverse events, and comparative effectiveness. Results We identified 14 articles with 413 patients treated with excision with primary closure and 233 patients treated with excision with closure by secondary intention. Pooled success rates were 95.7% with primary closure (95% confidence interval [CI]: 93.1% to 97.4%) and 92.7% with secondary intention (95% CI: 88.4% to 95.4%). Subcutaneous emphysema or urgent airway problems were uncommon, occurring in 3.8% and 3.6% of patients, respectively. Five studies had data suitable for comparative meta‐analysis, which showed no differences by closure technique for treatment success ( P = .480), overall complications ( P = .551), need for revision surgery ( P = .624), or the incidence of subcutaneous emphysema or pneumothorax ( P = .512), urgent airway problems ( P = .126), wound infection ( P = 1.00), or wound dehiscence or fistula ( P = .818). Conclusions There are no differences in the rates of success or complications with surgical closure of TCF in children, whether performed by primary closure or by secondary intention. Both techniques have high success rates with a low incidence of serious complications. Laryngoscope , 127:241–246, 2017

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here