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Staged laryngeal reconstruction with a prefabricated flap for radiation recurrent glottic carcinoma
Author(s) -
Mourad Moustafa W.,
Su Henry K.,
Castro Jerry R.,
Lazarus Cathy L.,
Clain Jason B.,
Mojica Jacqueline S.,
Urken Mark L.
Publication year - 2016
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.25593
Subject(s) - medicine , laryngectomy , surgery , salvage therapy , salvage surgery , stage (stratigraphy) , radiation therapy , laryngeal neoplasm , cancer , larynx , paleontology , chemotherapy , biology
Objectives/Hypothesis Although salvage total laryngectomy remains the definitive approach to recurrent/persistent glottic cancer following failed radiation therapy for favorable early‐stage disease, it comes at the price of a permanent laryngostome and an impact on quality of life. We describe a three‐stage method of laryngeal reconstruction for salvage partial laryngectomy to address the unique challenges of operating on radiation recurrent/persistent cancer. Study Design This was a single‐surgeon retrospective case series of patients who underwent a three‐stage laryngeal reconstruction for salvage partial laryngectomy. Methods We performed a comprehensive review of the clinical, pathologic, and radiologic files of all patients who underwent a three‐stage laryngeal reconstruction for salvage partial laryngectomy. Results Seven male patients underwent a three‐stage laryngeal reconstruction following open partial salvage laryngectomy. The average follow‐up time since salvage surgery was 55 months. All patients were without evidence of recurrence and demonstrated satisfactory functional outcomes. Conclusion Staged reconstruction provides a more controlled assessment of wound healing and valuable pathologic information regarding the specific disease virulence and adequacy of the margins. Level of Evidence 4. Laryngoscope , 126:1061–1070, 2016