Endoscope‐assisted transoral removal of a thyroglossal duct cyst using a frenotomy incision: A prospective clinical trial

Objectives/Hypothesis Endoscope‐assisted transoral removal of a thyroglossal duct cyst (TGDC) has been introduced to clinical practice. However, the technical feasibility, efficacy, and safety of this procedure have not been studied. Herein, we conducted a prospective clinical trial to evaluate endoscope‐assisted transoral removal of a TGDC. Study Design Prospective cohort study. Methods Thirty patients were included. We performed endoscope‐assisted transoral removal of TGDCs and evaluated the clinical results and complications over more than 2 years. Results Endoscope‐assisted transoral resection was successful in all cases. However, transient morbidity was noted in one patient. The mean operation time was 67.33 ± 17.26 minutes. Surgery was not required for recurrence or revision during a follow‐up. Conclusions Endoscope‐assisted transoral resection of a TGDC is a potentially safe and effective procedure leading to excellent functional and cosmetic outcomes. Additionally, considering the embryological development of TGDCs, the transoral approach can open a new access route to these cysts. Level of Evidence 2b. Laryngoscope , 125:2730–2735, 2015