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Minocycline‐induced hyperpigmentation of tympanic membrane, sclera, teeth, and pinna
Author(s) -
Reese Stephen,
Grundfast Kenneth
Publication year - 2015
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.25365
Subject(s) - medicine , hyperpigmentation , minocycline , sclera , pinna , sensorineural hearing loss , surgery , dermatology , hearing loss , audiology , microbiology and biotechnology , biology , antibiotics
A 40‐year‐old woman was referred by her primary care physician for evaluation after a routine physical exam revealed bilateral brownish pigmentation of the tympanic membrane. Head and neck examination in the otolaryngology clinic revealed bluish hue of both sclera, teeth, and portions of her pinnae. A hearing test revealed bilateral mild sensorineural hearing loss. The patient had a history of taking minocycline for 14 years, and the hyperpigmentation that she had is known to be a rare complication of prolonged minocycline use. However, to our knowledge, this is the first case showing photographic evidence of minocycline‐induced tympanic membrane hyperpigmentation. Minocycline‐induced hyperpigmentation should be considered when a patient presents with brown or blue discoloration of the tympanic membrane. Laryngoscope , 125:2601–2603, 2015