Premium
Can surgeons predict the olfactory outcomes after endoscopic surgery for nasal polyposis?
Author(s) -
Nguyen Duc Trung,
Bey Ayoub,
Arous Fabien,
NguyenThi PhiLinh,
FelixRavelo Marylisa,
Jankowski Roger
Publication year - 2015
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.25223
Subject(s) - medicine , olfactory system , anosmia , confidence interval , logistic regression , surgery , odds ratio , endoscopic sinus surgery , olfactory marker protein , hyposmia , prospective cohort study , olfactory epithelium , disease , psychiatry , infectious disease (medical specialty) , covid-19
Objectives/Hypothesis The aim of this study is to identify predictors for olfactory outcomes in patients with nasal polyposis (NP) after surgery on the ethmoidal labyrinths, either with or without resection of the polyps of the olfactory cleft (OC). Study Design Prospective study. Methods Ninety‐six patients endoscopically operated on for NP were enrolled in this study. Olfactory measurements were performed 1 day prior to surgery and 6 weeks after surgery, using odor thresholds and identification tests of the Sniffin' Sticks kit and a 0‐ to 10‐point visual analog scale. The multivariate logistic regression model was also used to assess independent predictors for olfactory outcomes after surgery. Results Twenty‐seven patients with preoperative normosmia demonstrated normal olfactory function 6 weeks after surgery. Out of 69 patients with preoperative hypo‐anosmia, 33 patients (47.83%) improved their olfactory function after surgery on the basis of the Sniffin' Sticks results. History of previous sinus surgery was reported by 77.78% of patients without olfactory improvement and by 51.52% with olfactory improvement ( P = .022). By multivariate analysis, history of previous sinus surgery for NP remained a strong predictor of poor olfactory outcomes after surgery (adjusted odds ratio = 4.14, 95% confidence interval: 1.29‐13.32, P = .017). Histopathological types of lesions inside the OC as well as the resection of moderate/big lesions in the OC were not predictors of olfactory outcomes. Conclusions The more previous sinus surgeries, the smaller the chance for patients to recover their olfactory function after each surgical revision. Level of Evidence 2b Laryngoscope , 125:1535–1540, 2015