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Dedifferentiated laryngeal chondrosarcoma: Combined morphologic and functional imaging with positron‐emission tomography/magnetic resonance imaging
Author(s) -
Purohit Bela S.,
Dulguerov Pavel,
Burkhardt Karim,
Becker Minerva
Publication year - 2014
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.24518
Subject(s) - positron emission tomography , magnetic resonance imaging , preclinical imaging , nuclear magnetic resonance , chondrosarcoma , tomography , functional imaging , positron emission , brain positron emission tomography , medicine , nuclear medicine , materials science , physics , radiology , in vivo , microbiology and biotechnology , biology
Chondrosarcoma of the larynx is a rare, low‐grade malignancy in terms of histology and clinical behavior. We present an unusual case of laryngeal chondrosarcoma, which developed a large dedifferentiated component on recurrence after primary surgery. The diagnosis of dedifferentiation was suggested in view of the morphological and metabolic findings on hybrid positron‐emission tomography/magnetic resonance imaging (PET/MRI) and was subsequently confirmed surgically. Whole‐organ, slice‐by‐slice radiologic–histologic correlation revealed excellent delineation of the well‐differentiated and dedifferentiated tumor components with PET/MRI. PET/MRI can provide additional functional information to supplement the morphological mapping and histopathology of these tumors.Laryngoscope , 124:E274–E277, 2014