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Rosai‐dorfman disease with extranodal involvement
Author(s) -
Hashimoto Kaori,
Kariya Shin,
Onoda Tomoo,
Ooue Tetsuo,
Yamashita Yasuhiko,
Naka Kikuko,
Okano Mitsuhiro,
Nishizaki Kazunori
Publication year - 2014
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.24290
Subject(s) - rosai–dorfman disease , medicine , cervical lymphadenopathy , biopsy , pathology , disease , bone marrow , lymph node , cervical lymph nodes , radiology , metastasis , cancer
Rosai‐Dorfman disease is a rare condition of marrow hematopoietic stem‐cell origin. Patients can show extranodal involvement as well as lymphatic involvement, but only about 5% of extranodal cases involve intracranial lesions. A 53‐year‐old male was admitted to our hospital with bilateral cervical lymphadenopathy. Intracranial tumors and bone lesions were also detected. Cervical lymph node biopsy and intracranial tumor resection were performed, and histopathological examination revealed Rosai‐Dorfman disease. The patient showed good clinical course without significant enlargement of the tumor. This study describes the case of a patient with Rosai‐Dorfman disease presenting with massive cervical lymphadenopathy mimicking malignant neoplasm. Laryngoscope , 124:701–704, 2014