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Long‐term results of endoscopic sinus surgery–oriented treatment for chronic rhinosinusitis with asthma
Author(s) -
Chen FengHong,
Zuo KeJun,
Guo YuBiao,
Li ZhiPing,
Xu Geng,
Xu Rui,
Shi JianBo
Publication year - 2014
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.24196
Subject(s) - medicine , asthma , chronic rhinosinusitis , functional endoscopic sinus surgery , pulmonary function testing , corticosteroid , prospective cohort study , endoscopy , surgery , sinusitis , cohort , visual analogue scale , anesthesia
Objectives/Hypothesis The aims of this study were to evaluate the efficacy of functional endoscopic sinus surgery (FESS)–oriented multimodality treatment in chronic rhinosinusitis (CRS) patients with asthma and its impact on asthma. Study Design Prospective, nonrandomized cohort. Methods Twenty‐seven CRS patients with asthma who underwent FESS with postoperative topical corticosteroid spray were evaluated preoperatively; 25 of them were evaluated 1 year and 3 years postoperatively. CRS was evaluated by visual analogue scale, clinical control of CRS, and objective measurement endoscopy Lund‐Kennedy scores. Asthma was assessed by subjective asthma control test and asthma control level, also by objective antiasthma medication use and pulmonary function tests. Results VAS scores of general symptoms (8.09 ± 0.87 preoperatively) were significantly improved at 1 year (2.94 ± 2.21) and 3 years (3.77 ± 2.16) postoperation ( P = .000). No difference in these items was found between 1 year and 3 years ( P = .463). Endoscopy Lund‐Kennedy scores at 1 year (4.34 ± 3.09) and 3 years (5.80 ± 3.38) postoperatively were significantly better (9.33 ± 2.03 preoperatively, P = .000), and there was no difference between 1 year and 3 years of follow‐up ( P > .05). Significantly, asthma control level improved postoperatively ( P = .025). However, antiasthma drug and pulmonary function showed no significant change postoperatively ( P > .05). Conclusions FESS‐oriented multimodality treatment improves CRS with asthma significantly and persistently. Asthma control level improved. Antiasthma medication use and pulmonary function remained stable. Level of Evidence 4. Laryngoscope , 124:24–28, 2014