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Transoral laser microsurgery for early glottic cancer as one‐stage single‐modality therapy
Author(s) -
Lee Hyoung Shin,
Chun BongGwon,
Kim Sung Won,
Kim Seung Tae,
Oh Jung Ho,
Hong Jong Chul,
Lee Kang Dae
Publication year - 2013
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.24080
Subject(s) - transoral laser microsurgery , stage (stratigraphy) , modality (human–computer interaction) , medicine , microsurgery , laser therapy , single stage , surgery , laser , radiation therapy , computer science , head and neck cancer , artificial intelligence , engineering , optics , geology , physics , aerospace engineering , paleontology
Objectives/Hypothesis A study was undertaken to determine the oncologic outcomes in a consecutive series of early glottic carcinomas treated with transoral CO 2 laser microsurgery (TLM) as a one‐stage single‐modality therapy, without any postoperative radiation therapy or retreatment with laser. We further evaluated correlations between the oncologic outcomes and clinicopathologic factors including tumor location and surgical margin. Study Design Retrospective analysis of medical records. Methods The medical records of 118 consecutive patients with early stage (T1, T2) glottic carcinoma who underwent TLM by a single surgeon as an initial treatment from 1997 to 2011 were retrospectively reviewed. The oncologic outcomes were evaluated, and correlations to clinicopathologic factors were analyzed. Results The 5‐year disease‐free survival, ultimate local control with laser alone, disease‐specific survival, overall survival, and organ preservation rates were 87.9%, 94.2%, 99.0%, 92.2%, and 96.2%, respectively. Neither the reported surgical margin nor the extension of tumor to the anterior commissure, arytenoid, subglottis, and ventricle showed any significant impact on local control or survival. Conclusions Transoral CO 2 laser microsurgery as one‐stage single‐modality therapy resulted in a high rate of local control and a high survival rate in selected cases of early glottic carcinoma, regardless of the location of tumor and histopathology report on the surgical margin. Level of Evidence 4 Laryngoscope , 123:2670–2674, 2013