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Delayed lower cranial neuropathies following primary radiotherapy for oropharyngeal squamous cell carcinoma
Author(s) -
Huang Andrew T.,
Song Shiyu,
Dominguez Laura M.,
Nguyen Josephine,
Goldman Richard A.,
Reiter Evan R.
Publication year - 2013
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.23938
Subject(s) - medicine , swallowing , radiation therapy , complication , nasopharyngeal carcinoma , head and neck cancer , head and neck , basal cell , adverse effect , cancer , surgery
Objectives/Hypothesis Delayed lower cranial neuropathy is a rare complication following primary radiotherapy for head and neck cancer, and has been most associated with nasopharyngeal carcinoma with minimal data regarding this outcome in the treatment of the oropharynx. No reports, to the authors' knowledge, have described this complication following intensity modulated radiation therapy (IMRT) for oropharyngeal primaries. Once encountered, this adverse outcome can have serious impacts on speech and swallowing. We present here our institution's experience with delayed cranial neuropathies following primary radiation therapy for oropharyngeal squamous cell carcinoma, as well as document the only reported case following IMRT.