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Primary surgical treatment of T3 glottic carcinoma: Long‐term results and decision‐making aspects
Author(s) -
Mantsopoulos Konstantinos,
Psychogios Georgios,
Bohr Christopher,
Zenk Johannes,
Kapsreiter Markus,
Waldfahrer Frank,
Iro Heinrich
Publication year - 2012
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.23580
Subject(s) - term (time) , carcinoma , medicine , glottis , primary (astronomy) , oncology , surgery , general surgery , larynx , physics , quantum mechanics , astronomy
Objectives/Hypothesis: The aim of this study was to assess the efficacy of primary surgical treatment in the management of T3 glottic carcinomas. Study Design: Retrospective clinical study. Methods: A retrospective evaluation of the records for all patients treated with primary surgery for T3 glottic carcinomas at a tertiary referral center between 1980 and 2005 was carried out. Data for the 5‐year disease‐specific survival (DSS) were assessed, as well as local control rates in relation to vocal cord immobility, N classification, choice of surgical modality, and adjuvant therapy. Patients who underwent partial laryngectomy were also evaluated in relation to organ preservation and the rate of permanent tracheotomies. Results: The 5‐year DSS in the 120 patients was 78.3%. Positive neck disease was shown to be a significant negative prognostic factor. Organ preservation was achieved in 90.1% of the patients who underwent partial laryngectomy and in 50% of the overall patient group. The occult metastasis rate was 14%. Conclusions: Primary surgical treatment is an effective modality against T3 glottic carcinomas. Partial laryngectomy is a reliable method in carefully selected cases. Low complication rates can be expected. Laryngoscope, 2012