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Ex vivo high resolution imaging with a miniaturized microendoscope to discriminate between benign and malignant mucosa in the upper aerodigestive tract
Author(s) -
Levy Lauren,
Smith Claris,
Gurudutt Vivek,
Teng Marita,
Rivera Michael,
Anadasabapathy Sharmila,
Genden Eric,
Gillenwater Ann,
RichardsKortum Rebecca,
Sikora Andrew
Publication year - 2010
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.21626
Subject(s) - otorhinolaryngology , head and neck surgery , medicine , mount , general surgery , surgery , computer science , operating system
•Continued refinement of this optical imaging technology may lead to improved ability to accurately determine optical margins, facilitate the sparing of uninvolved normal tissue, and find application to novel technological platforms, such as robotic surgery. Figure 1. High Resolution Microendoscope (HRME). The device consists of a fiber-optic bundle which can deliver high resolution narrow field images of tissue morphology. The image is magnified by a microscope objective. Surface staining with a nuclear dye is required to display the morphology of the epithelial nuclei.