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Diagnosis of the extent of advanced oropharyngeal and hypopharyngeal cancers by narrow band imaging with magnifying endoscopy
Author(s) -
Matsuba Hiroki,
Katada Chikatoshi,
Masaki Takashi,
Nakayama Meijin,
Okamoto Tabito,
Hanaoka Noboru,
Tanabe Satoshi,
Koizumi Wasaburo,
Okamoto Makito,
Muto Manabu
Publication year - 2011
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.21553
Subject(s) - hypopharyngeal cancer , medicine , cancer , esophageal cancer , stage (stratigraphy) , endoscopy , radiology , esophagus , paleontology , biology
Objectives/Hypothesis: Narrow band imaging combined with magnifying endoscopy (NBI‐ME) is useful for the detection of superficial cancer in the oropharynx, hypopharynx, and esophagus. We used NBI‐ME to evaluate the frequency of superficial cancer spread (SCS) contiguous with advanced oropharyngeal and hypopharyngeal cancers and esophageal cancers. Study Design: Retrospective. Methods: We retrospectively studied 45 patients with oropharyngeal and hypopharyngeal cancer and 44 with esophageal cancer who underwent NBI‐ME from October 2006 through April 2009. The following variables were evaluated: 1) the frequency of SCS contiguous with advanced oropharyngeal and hypopharyngeal cancer and esophageal cancer, and 2) the influence of SCS contiguous with advanced oropharyngeal and hypopharyngeal cancer on clinical T category and clinical stage. Results: SCS contiguous with the primary tumor was found in 49% (22/45) of the patients with advanced oropharyngeal and hypopharyngeal cancer and in 52% (23/44) of those with advanced esophageal cancer. When SCS contiguous with the primary tumor was included in the evaluation of tumor size in advanced oropharyngeal and hypopharyngeal cancer, the clinical T category and clinical stage were revised in 20% (9/45) and 4% (2/45) of patients, respectively; SCS was ≤2 cm in 64% of cases (14/22) and between >2 cm and ≤4 cm in 36% (8/22). Conclusions: NBI‐ME should be included in the pretreatment diagnostic work‐up to evaluate lesion extent and decide optimal surgical margins and radiation fields in patients with advanced oropharyngeal and hypopharyngeal cancer. Laryngoscope, 2011