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The Role of Proton Pump Inhibitors in Reducing Laryngeal Injury During Prolonged Intubation
Author(s) -
deSilva Brad W.,
Trudeau Michael D.,
Forrest L. Arick
Publication year - 2009
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.21522
Subject(s) - medicine , otorhinolaryngology , swallowing , general surgery , head and neck surgery , surgery
Methods: Adult subjects were prospectively enrolled and underwent video-recorded transnasal fiberoptic laryngoscopy following extubation in the medical intensive care unit. Variables recorded include: duration of intubation, size of endotracheal tube, and administration of proton pump inhibitor versus H-2 blocker during intubation. The laryngoscopy examinations were blindly reviewed and laryngeal injuries that were documented include: presence of vocal fold immobility, vocal fold granuloma, and laryngeal erythema or ulceration.