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Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: A Case Report
Author(s) -
Di Nardo Walter,
Cattani Paola,
Scorpecci Alessandro,
Giannantonio Sara,
D'Onghia Sara,
Fadda Giovanni,
Paludetti Gaetano
Publication year - 2011
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.21447
Subject(s) - perilymph , cytomegalovirus , cochlea , inner ear , polymerase chain reaction , audiology , medicine , cochlear implant , virology , biology , virus , herpesviridae , genetics , viral disease , anatomy , gene
In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15‐month‐old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection. Laryngoscope, 2011