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Sarcoidosis of the thyroid: A case report and review of the literature
Author(s) -
Makowski Renee L.,
Peterson David J.,
O'Brien Kerry L.,
Harsha Wayne J.
Publication year - 2010
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.21222
Subject(s) - medicine , library science , center (category theory) , sarcoidosis , family medicine , chemistry , computer science , crystallography
Results: 67 year old male with lithiuminduced hypothyroidism and sarcoidosis presented with a thyroid nodule. Fine needle aspiration biopsy demonstrated atypical cellular features with epithelioid histiocytes found in loose syncitial aggregates and a background of lymphocytes, findings concerning for possibile papillary thyroid carcinoma. The final pathology from his thyroidectomy revealed multiple nodules and replacement of thyroid tissue with chronic inflammatory cells and a scattering of multiple well-formed interstitial non-caseating granulomas composed of epithelioid histiocytes, a mixed inflammatory infiltrate, and multinucleated giant cells. A lymph node further demonstrated multiple interstitial non-caseating granulomas composed of epithelioid histiocytes surrounded by mixed inflammatory infiltrate and multinucleated giant cells. The final diagnosis was sarcoidosis of the thyroid.