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A contemporary review of indications for primary surgical care of patients with squamous cell carcinoma of the head and neck
Author(s) -
Gourin Christine G.,
Johnson Jonas T.
Publication year - 2009
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.20619
Subject(s) - medicine , head and neck cancer , head and neck , surgery , basal cell , carcinoma , larynx , primary cancer , head and neck squamous cell carcinoma , cancer , radiation therapy , laryngeal neoplasm , gold standard (test) , randomized controlled trial , general surgery , radiology
The success of organ preservation protocols in laryngeal cancer has led to an increase in the use of primary chemoradiation in both laryngeal and extralaryngeal sites, despite a paucity of randomized controlled clinical trial data comparing nonoperative treatment to the gold standard of surgery followed by postoperative radiation for adverse pathologic features for head and neck cancer, and an increasing recognition that the high surgical salvage rates enjoyed by laryngeal cancer patients do not translate to extralaryngeal sites. These data suggest that there is a need to apply more rigorous standards to the use of organ preservation strategies and offer an opportunity to review the role of primary surgery in head and neck cancer. Laryngoscope, 2009