z-logo
Premium
Level V involvement in patients with early T‐stage, node‐positive oropharyngeal carcinoma
Author(s) -
Pattani Kavita M.,
Califano Joseph,
Sanguineti Giuseppe
Publication year - 2009
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.20616
Subject(s) - medicine , lymph node , subclinical infection , pathological , stage (stratigraphy) , dissection (medical) , chemoradiotherapy , neck dissection , nodal , carcinoma , surgery , radiation therapy , paleontology , biology
Objectives/Hypothesis: To assess the risk of level V nodal involvement for early T‐stage and node positive oropharyngeal squamous cell carcinoma (ORO‐SCC). Methods: Retrospective analysis performed on patients with ORO‐SCC and clinically positive lymph nodes who had undergone upfront elective dissection of level V before definitive chemoradiotherapy. Pathological data collected and prevalence of involvement of level V determined. Results: A total of 119 patients had level V dissection. The prevalence of pathologically positive lymph nodes in level V was 3.4% (4/119). Moreover, it was observed only in the presence of pathological involvement of multiple other nodal levels (4/52 patients, 7.7% vs. 0/67 in patients with a single nodal station involved, χ 2 P = .02). Conclusions: Subclinical involvement of level V in ORO‐SCC is rare, especially in the presence of disease confined to a single nodal level. The present data do not support its dissection after primary chemoradiotherapy. Laryngoscope, 2009

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here