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Intralesional bleomycin injections in the treatment of benign lymphoepithelial cysts of the parotid gland in HIV‐positive patients: Case reports
Author(s) -
Monama Glen M.,
Tshifularo Mashudu I.
Publication year - 2010
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.20577
Subject(s) - bleomycin , parotid gland , medicine , human immunodeficiency virus (hiv) , salivary gland , surgery , pathology , chemotherapy , immunology
Abstract Benign lymphoepithelial cysts (BLCs) of the parotid gland are associated with human immunodeficiency virus. These cysts may grow large and uncomfortable, causing significant cosmetic embarrassment for the patient. Several treatment options have been described with varying successes. We report successful treatment of three adults with bleomycin. All three patients presented with bilateral parotid enlargements. They received a total dose of between 180 U and 270 U of bleomycin over a period of 6 to 10 weeks. They all responded completely without morbidity or recurrence. Bleomycin is effective in the treatment of BLCs of the parotid glands in HIV‐positive patients. Laryngoscope, 2010