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A Modified Rabbit Model for the Endoscopic Creation and Study of Benign Tracheal Stenosis
Author(s) -
EgoOsuala Bryan C.,
Wright Richard J.,
Sewell Duane,
Meyer Tanya K.
Publication year - 2009
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.20387
Subject(s) - wright , id, ego and super ego , section (typography) , citation , presentation (obstetrics) , psychoanalysis , art history , medicine , psychology , computer science , art , library science , surgery , operating system
Our goal is to continue this study with the hope to start treating the tracheal stenoses we create using different modalities i.e. dilation, stenting, resection. The research aims are to: 1. Establish an endoscopic small animal model of airway stenosis. 2. Create a controlled, reproducible stenosis endoscopically. 3. Expand the armamentarium available to treat tracheal stenosis. Normal Bronchoscopy of Rabbit prior to beginning cautery Rabbits are an accepted model of airway stenosis and develop traumatically induced stenosis as seen in human subjects. To date, most of the work seen on the rabbit airway has been though a tracheotomy or laryngofissure to access the tracheal mucosa from an external approach to create the desired lesions. Treatment or interventions have been applied at the time of the initial lesioning to prevent or retard the development of the nascent stenosis. This model does not accurately reflect the clinical dilemma in which therapy attempts to mitigate a mature stenosis.