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Laser disruption and killing of mrsa biofilms
Author(s) -
Krespi Yosef P.,
Kizhner Victor,
Nistico Laura,
HallStoodley Luanne,
Stoodley Paul
Publication year - 2009
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.20367
Subject(s) - citation , section (typography) , library science , presentation (obstetrics) , computer science , medicine , operating system , radiology
Materials and Methods: Biofilms of S. aureus Xen 31, a stable bioluminescent clinical MRSA construct, were grown in a 96 well microtiter plate for three days. The study included seven arms; a) control, b) ciprofloxacin (0.3 mg/L,) alone, c) SW laser alone, d) NIR laser alone e) SW laser and ciprofloxacin, f) SW and NIR lasers, g) SW, NIR lasers and ciprofloxacin. The results were evaluated with an IVIS biophotonic system (for live bacteria) and optical density (for total bacteria).