z-logo
Premium
Vocal fold augmentation with calcium hydroxylapatite: Twelve‐month report
Author(s) -
Rosen Clark A.,
GartnerSchmidt Jackie,
Casiano Roy,
Anderson Timothy D.,
Johnson Felicia,
Remacle Marc,
Sataloff Robert T.,
Abitbol Jean,
Shaw Gary,
Archer Sanford,
Zraick Richard I.
Publication year - 2009
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.20126
Subject(s) - phonation , medicine , vocal fold paralysis , visual analogue scale , vocal folds , audiology , prospective cohort study , surgery , paralysis , larynx
Objectives: To evaluate the long‐term effectiveness of calcium hydroxylapatite (CaHA) vocal fold injection for patients with glottal insufficiency. Study Design: Multicenter, open‐label, prospective clinical study of CaHA vocal fold injection. Methods: Each patient served as his/her own control. Voice‐related outcome measures were collected for pre‐injection, 1, 3, 6, and 12 months. Results: Sixty‐three patients were available for evaluation. Fifty‐three percent of the injection procedures were done in the office. Fifty‐seven percent of patients were diagnosed with unilateral paralysis and 43% with glottal incompetence with mobile vocal folds. Patient satisfaction 12 months after injection showed 67% reporting a significant improvement in voice and 81% reporting at least a moderate improvement in voice. Utilizing the Voice Handicap Index–10, visual analog scale (vocal effort), Consensus Assessment Perceptual Evaluation V (judgments of voice severity), and objective voice measures of glottal closure (maximum phonation time and S:Z ratio), paired t tests showed significant improvements after treatment. A 22% further treatment rate was found at the 12‐month time point. Conclusions: One‐year results in this large cohort of patients with glottal incompetence treated with CaHA vocal fold injection demonstrate that excellent clinical results were achieved. Laryngoscope, 2009

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here