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Guidelines For Prognosis In Head And Neck Cancer With Nodal Metastasis
Author(s) -
Zoller Michae,
Goodman Max L.,
Cummings Charles W.
Publication year - 1978
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.1978.88.1.135
Subject(s) - medicine , nodal , head and neck , head and neck cancer , radiation therapy , host response , radiology , oncology , metastasis , cancer , inflammatory response , surgery , inflammation , immune system , immunology
Patients with squamous cell carcinoma of the head and neck with cervical node metastasis were studied retrospectively to delineate the prognostic significance of certain clinical and histologic parameters. The patients were divided into radiated and non‐radiated groups for analysis purposes. A good prognosis was found in non‐radiated patients with an active nodal plasmacytic inflammatory response. No prognostic information was obtainable in observing the inflammatory response of nodes altered by radiation effects. Extranodal spread of the tumor indicated a poor prognosis for radiated and non‐radiated patients, being more significant in the non‐radiated ones. Patients receiving preoperative radiation must be separated from nonradiated patients in evaluating host response parameters for prognostic purposes.