Premium
Determination of the rate of formation of the schiff bases of pyridoxal 5′‐phosphate with polyallylamine
Author(s) -
Del Vado M. Angeles Garcí,
Rodríguez Cardona Angel F.,
Echevarría Gerardo R.,
Santos Blanco José G.,
Zumel Consuelo López,
Blanco Francisco García
Publication year - 1995
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/kin.550270910
Subject(s) - chemistry , deprotonation , schiff base , pyridoxal , ionic strength , catalysis , acetic acid , pyridoxal 5 phosphate , phosphate , inorganic chemistry , polymer chemistry , organic chemistry , ion , aqueous solution
The formation constants of the Schiff bases of pyridoxal 5′‐phosphate with polyallylamine were determined over the p H range of the acetic‐acetate buffer (3.9–5.5) at an ionic strength of 0.1 M and a temperature of 25°C. The results were consistent with the rapid formation of an ionized carbinolamine, T + , followed by deprotonation, in the rate‐determining step, to a neutral carbinolamine, T °. Subsequent dehydration of T ° in a rapid step yields the final Schiff base. The formation of T + is a concerted process subject to specific acid catalysis. © 1995 John Wiley & Sons, Inc.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom