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Nitrenium ions in N‐chloro‐α‐amino acids decomposition?
Author(s) -
Armesto X. L.,
Canle L. M.,
Losada M.,
Santaballa J. A.
Publication year - 1993
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/kin.550250102
Subject(s) - chemistry , decomposition , kinetics , leucine , aqueous solution , amino acid , ion , isoleucine , medicinal chemistry , computational chemistry , stereochemistry , organic chemistry , biochemistry , physics , quantum mechanics
This article deals with the kinetics of decomposition of four isomers: NCl‐(L)‐2‐Aminohexanoic acid, NCl‐(L)‐Leucine, NCl‐(L)‐Isoleucine, and NCl‐(L)‐ tert ‐Leucine, in mild acid and basic aqueous solution. An alternative mechanism for this process which takes place through a nitrenium‐like ion transition state is proposed. This mechanism is in consonance with the experimental data and with those available from the literature. © 1993 John Wiley & Sons, Inc.