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Oxidation with permanganate in strong alkaline medium. Oxidation of pyruvic and lactic acids
Author(s) -
Jáky Miklós,
Kozhevnikov Ivan V.,
HÖFt Eugen
Publication year - 1992
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/kin.550241204
Subject(s) - chemistry , permanganate , deprotonation , pyruvic acid , lactic acid , inorganic chemistry , adduct , aqueous solution , alkoxy group , medicinal chemistry , reaction rate constant , hydrate , ion , organic chemistry , kinetics , alkyl , genetics , physics , quantum mechanics , biology , bacteria
The reaction of permanganate ion with pyruvic acid and lactic acid has been studied in aqueous solutions containing 0.10–2.0 mol dm −3 alkali. In this range of HO − concentration the reaction\documentclass{article}\pagestyle{empty}\begin{document}$$ 2{\rm MnO}_4 ^- + {\rm Substrate} \to {\rm 2MnO}_{\rm 4} ^{2-} + {\rm product} $$\end{document} is followed slowly by the reduction of manganate, thus, the above process can be studied separately. In the case of lactic acid (LA), the reactive species is alkoxy anion, and the deprotonation constant could be calculated from the kinetic data. A mechanism based on electron abstraction from the alkoxy anion has been proposed. In the case of pyruvic acid (PA) oxidation may proceed with participation of enolate anion, or hydrate anion, or an adduct. These three possibilities have been investigated. © John Wiley & Sons, Inc.