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Reactions of halogenated organic peroxyl radicals with various purine derivatives, tyrosine, and thymine: A pulse radiolysis study
Author(s) -
Kapoor Sudhir Kumar,
Gopinathan C.
Publication year - 1992
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/kin.550241202
Subject(s) - chemistry , radiolysis , radical , thymine , reaction rate constant , xanthine , guanosine , photochemistry , guanine , hypoxanthine , aqueous solution , medicinal chemistry , kinetics , organic chemistry , nucleotide , biochemistry , enzyme , dna , physics , quantum mechanics , gene
Absolute rate constants for the one electron oxidation of guanine, guanosine, uric acid, xanthine, hypoxanthine, tyrosine, and thymine by various halogenated peroxyl radicals in aqueous solutions have been determined using the technique of pulse radiolysis. Roughly, linear correlations have been observed between the logarithm of these rate constants and Taft's inductive parameter (σ*) for the radicals. However, the rate constants for the radical CBr 3 O 2 ˙are slightly higher than those for CCl 3 O 2 ˙for most of these compounds. © John Wiley & Sons, Inc.