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Micellar hydrolysis of hydroxamic acids. Michaelis‐menten kinetics
Author(s) -
Berndt Donald C.,
Angus Jill E.,
Wood Michael J.,
Atkinson Richard F.,
Qureshi Tanveer A.,
Shay Brian J.,
Provancher Aura I.
Publication year - 1989
Publication title -
international journal of chemical kinetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.341
H-Index - 68
eISSN - 1097-4601
pISSN - 0538-8066
DOI - 10.1002/kin.550210606
Subject(s) - chemistry , hydroxamic acid , bromide , kinetics , hydrolysis , michaelis–menten kinetics , substrate (aquarium) , reaction rate , enzyme kinetics , organic chemistry , enzyme , catalysis , enzyme assay , active site , physics , oceanography , quantum mechanics , geology
Rates of reaction for the alkaline hydrolysis of various hydroxamic acids in the presence of cetyltrimethylammonium bromide have been determined. Empirical reaction orders of zero, one‐half, and one were found for the hydroxamic acids depending upon reaction conditions and substrate structure. N ‐methylhydroxamic acids exhibited only first‐order kinetics. The results are consistent with the Michaelis‐Menten rate equation.